LOWVELO / [ low·vel·oh ] / Noun. A combination of the words Lowcountry and velo, the French word for “bike.” A cycling event that brings a dedicated group of riders, volunteers, virtual participants, sponsors and staff members together to raise funds for innovative and lifesaving cancer research at the state’s only National Cancer Institute-designated cancer center: MUSC Hollings Cancer Center in Charleston.
Get ready to ride!
LOWVELO brings individuals, communities and organizations together on November 1, 2025. In the process, we’re creating amazing memories and honoring cancer survivors and loved ones lost. But LOWVELO isn’t just a one day event – it’s a lifestyle!
We have events running all year long to help you get your mind and body ready to ride and to support other teams, riders, and researchers who make LOWVELO one of the best events in Charleston.
LOWVELO is for everyone
LOWVELO offers participants a choice of five cycling routes to experience beautiful Lowcountry landscapes. We also have a stationary ride and the virtual LOWVELO Home Team option for those who can’t join us in person or who prefer to cycle, walk, or run on their own.
We’ll give you inspiration along the way to train and create a healthier lifestyle — yet another way to fulfill our mission of cancer prevention and awareness. Want to participate in LOWVELO but not as a rider? Become a LOWVELO volunteer!
100% dedicated to cancer research
When you participate in LOWVELO, you know where your money goes. All of your hard work goes directly to support lifesaving cancer research happening at MUSC Hollings Cancer Center.
LOWVELO24 Recap: A record-breaking ride!
What a ride! LOWVELO24 was our biggest event yet with a record-breaking 1,895 riders, 267 volunteers, and $1,002,000 raised for lifesaving and innovative cancer research at MUSC Hollings Cancer Center!
Whether you are riding, donating, or volunteering, your support makes a big impact on lifesaving cancer research at Hollings. Check out our blog, the Hollings News Center and our videos for the latest updates about our amazing researchers and participants.
Join the cause
Registration for LOWVELO25 is now open. Participation includes a LOWVELO25 T-shirt and swag bag as well as admission to the Packet Pick-up Party at Firefly Distillery, Finish Line Block Party after the ride and the LOWVELO25 Awards Ceremony in early 2026. Riders who register for the 23-, 50- and 80-mile routes also get a cycling jersey.
Top Participants
Top Teams
Since LOWVELO first took hold in 2019, we’ve been amazed at how our community has come together to raise money for cancer research and make a difference in the lives of those affected by cancer. Events like this really do make a difference in the fight against a disease that touches so many.
Dr. Raymond N. DuBois
MUSC Hollings Cancer Center director
LOWVELO25 Countdown
Presenting Sponsor
